{"id":49,"date":"2017-11-27T15:25:10","date_gmt":"2017-11-27T12:25:10","guid":{"rendered":"http:\/\/spiporz.ru\/fabri1\/?page_id=49"},"modified":"2017-11-27T19:23:14","modified_gmt":"2017-11-27T16:23:14","slug":"nervnaya-sistema","status":"publish","type":"page","link":"https:\/\/spiporz.ru\/fabry\/nervnaya-sistema\/","title":{"rendered":"\u041d\u0435\u0440\u0432\u043d\u0430\u044f \u0441\u0438\u0441\u0442\u0435\u043c\u0430"},"content":{"rendered":"

\u0421\u0438\u043b\u044c\u043d\u0430\u044f \u0438\u0437\u043d\u0443\u0440\u044f\u044e\u0449\u0430\u044f \u043d\u0435\u0432\u0440\u043e\u043f\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u043e\u043b\u044c \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0447\u0430\u0441\u0442\u044b\u043c \u0440\u0430\u043d\u043d\u0438\u043c \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u043c \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0424\u0430\u0431\u0440\u0438, \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u043c\u044b\u043c \u043f\u043e\u0447\u0442\u0438 \u0443 77% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432. (* 1) \u0411\u043e\u043b\u044c \u043e\u0431\u044b\u0447\u043d\u043e \u043e\u0449\u0443\u0449\u0430\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u0430\u043a\u0440\u043e\u043f\u0430\u0440\u0435\u0441\u0442\u0435\u0437\u0438\u044f (\u0447\u0443\u0432\u0441\u0442\u0432\u043e \u0436\u0436\u0435\u043d\u0438\u044f, \u043f\u043e\u043a\u0430\u043b\u044b\u0432\u0430\u043d\u0438\u044f \u0438\u043b\u0438 \u043e\u043d\u0435\u043c\u0435\u043d\u0438\u044f \u043a\u043e\u043d\u0435\u0447\u043d\u043e\u0441\u0442\u0435\u0439); \u043e\u0442\u043c\u0435\u0447\u0430\u044e\u0442\u0441\u044f \u0442\u0430\u043a\u0436\u0435 \u043f\u0440\u0438\u0441\u0442\u0443\u043f\u044b \u043e\u0441\u0442\u0440\u043e\u0439 \u0438\u043b\u0438 \u0436\u0433\u0443\u0447\u0435\u0439 \u0431\u043e\u043b\u0438. (*1; 2; 3) \u0418\u043c\u0435\u0435\u0442\u0441\u044f \u0442\u0435\u043d\u0434\u0435\u043d\u0446\u0438\u044f \u043a \u043d\u0430\u0447\u0430\u043b\u0443 \u0431\u043e\u043b\u0435\u0439 \u0441 \u043b\u0430\u0434\u043e\u043d\u0435\u0439 \u0438 \u043f\u043e\u0434\u043e\u0448\u0432 \u0441 \u0434\u0430\u043b\u044c\u043d\u0435\u0439\u0448\u0438\u043c \u043f\u0440\u043e\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u044b\u043c \u0438\u0445 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u0435\u043c. (*3) \u0411\u043e\u043b\u0435\u0432\u044b\u0435 \u043a\u0440\u0438\u0437\u044b \u043c\u043e\u0433\u0443\u0442 \u043f\u0440\u043e\u0432\u043e\u0446\u0438\u0440\u043e\u0432\u0430\u0442\u044c\u0441\u044f \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c\u044e, \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0435\u043c \u0442\u0435\u043c\u043f\u0435\u0440\u0430\u0442\u0443\u0440\u044b \u043e\u043a\u0440\u0443\u0436\u0430\u044e\u0449\u0435\u0439 \u0441\u0440\u0435\u0434\u044b \u0438\u043b\u0438 \u0441\u0442\u0440\u0435\u0441\u0441\u043e\u043c. (*1)<\/p>\n

\u0422\u0430\u043a\u0436\u0435 \u0447\u0430\u0441\u0442\u044b\u043c \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u043c \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0441\u043d\u0438\u0436\u0435\u043d\u043d\u043e\u0435 \u043f\u043e\u0442\u043e\u043e\u0442\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0438\u043b\u0438 \u0435\u0433\u043e \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0438\u0435, \u0438 \u044d\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u043f\u0440\u0438\u0447\u0438\u043d\u043e\u0439 \u043f\u043b\u043e\u0445\u043e\u0439 \u043f\u0435\u0440\u0435\u043d\u043e\u0441\u0438\u043c\u043e\u0441\u0442\u0438 \u0436\u0430\u0440\u044b \u0438 \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043d\u0430\u0433\u0440\u0443\u0437\u043e\u043a. (*3; 4)<\/p>\n

\u041b\u0438\u0442\u0435\u0440\u0430\u0442\u0443\u0440\u0430:<\/p>\n

    \n
  1. MacDermot KD, Holmes A, Miners AH. Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 98 hemizygous males. Journal of Medical Genetics 2001; 38: 750-760.<\/li>\n
  2. Mehta A, Ricci R, Widmer U, Dehout F, Garcia de Lorenzo A, Kampmann C, et al. Fabry disease defined: baseline clinical manifestations of 366 patients in the Fabry Outcome Survey. European Journal of Clinical Investigation 2004; 34: 236-242.<\/li>\n
  3. Hughes DA, Ramaswami U, Elliott, P, Deegan P, Lee P, Waldek S, et al. Guidelines for the diagnosis and management of Anderson-Fabry disease. Department of Health, 2005.<\/li>\n
  4. Schiffmann R, Floeter MK, Dambrosia JM, Gupta S, Moore DF, Sharabi Y, et al. Enzyme replacement therapy improves peripheral nerve and sweat function in Fabry disease. Muscle & Nerve 2003; 28: 703-710.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    \u0421\u0438\u043b\u044c\u043d\u0430\u044f \u0438\u0437\u043d\u0443\u0440\u044f\u044e\u0449\u0430\u044f \u043d\u0435\u0432\u0440\u043e\u043f\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u043e\u043b\u044c \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0447\u0430\u0441\u0442\u044b\u043c \u0440\u0430\u043d\u043d\u0438\u043c \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u043c \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0424\u0430\u0431\u0440\u0438, \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u043c\u044b\u043c \u043f\u043e\u0447\u0442\u0438 \u0443 77% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432. (* 1) \u0411\u043e\u043b\u044c \u043e\u0431\u044b\u0447\u043d\u043e \u043e\u0449\u0443\u0449\u0430\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u0430\u043a\u0440\u043e\u043f\u0430\u0440\u0435\u0441\u0442\u0435\u0437\u0438\u044f (\u0447\u0443\u0432\u0441\u0442\u0432\u043e \u0436\u0436\u0435\u043d\u0438\u044f, \u043f\u043e\u043a\u0430\u043b\u044b\u0432\u0430\u043d\u0438\u044f \u0438\u043b\u0438 \u043e\u043d\u0435\u043c\u0435\u043d\u0438\u044f \u043a\u043e\u043d\u0435\u0447\u043d\u043e\u0441\u0442\u0435\u0439); \u043e\u0442\u043c\u0435\u0447\u0430\u044e\u0442\u0441\u044f \u0442\u0430\u043a\u0436\u0435 \u043f\u0440\u0438\u0441\u0442\u0443\u043f\u044b \u043e\u0441\u0442\u0440\u043e\u0439 \u0438\u043b\u0438 \u0436\u0433\u0443\u0447\u0435\u0439 \u0431\u043e\u043b\u0438. (*1; 2; 3) \u0418\u043c\u0435\u0435\u0442\u0441\u044f \u0442\u0435\u043d\u0434\u0435\u043d\u0446\u0438\u044f \u043a \u043d\u0430\u0447\u0430\u043b\u0443 \u0431\u043e\u043b\u0435\u0439 \u0441 \u043b\u0430\u0434\u043e\u043d\u0435\u0439 \u0438 \u043f\u043e\u0434\u043e\u0448\u0432 \u0441 \u0434\u0430\u043b\u044c\u043d\u0435\u0439\u0448\u0438\u043c \u043f\u0440\u043e\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u044b\u043c \u0438\u0445 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u0435\u043c. (*3) \u0411\u043e\u043b\u0435\u0432\u044b\u0435 \u043a\u0440\u0438\u0437\u044b…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"class_list":["post-49","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/pages\/49","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/comments?post=49"}],"version-history":[{"count":2,"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/pages\/49\/revisions"}],"predecessor-version":[{"id":78,"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/pages\/49\/revisions\/78"}],"wp:attachment":[{"href":"https:\/\/spiporz.ru\/fabry\/wp-json\/wp\/v2\/media?parent=49"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}